研究成果
主持和主参的科研项目:
1. 国家新药创制重大专项,2017ZX09301007,基于小麦醇溶蛋白纳米制剂关键技术中药新药-杞芍颗粒的研究,2017/01-2020/12。
2. 浙江省重点研发计划,2017C02G1321006,浙产特色药材质量安全控制技术研究与示范—铁皮石斛、浙贝母和灵芝浙产特色药材质量控制技术研究与示范,2018/01-2020/12。
3. 国家自然科学基金项目,81703634,浙江常用中药圆锥铁线莲多酚氧化酶响应紫外诱导催化香豆素生物合成的机制研究,2018/01-2020/12。
4. 浙江省科技厅一带一路项目,2016C04005,浙江-马来西亚传统药物联合研究中心,2016/01-2190/12。
5. 国家新药创制重大专项,2012ZX09102-201-010,抗肿瘤新药开培瑞胶囊的临床前研究(滚动),2012/01-2015/12。
6. 国家自然科学基金面上项目,81073155,光酶诱导桑叶中具有抗炎活性的Diels-Alder型加合物生物合成机制研究,2011/01-2013/12。
7. 国家自然科学基金面上项目,31060272,灰树花GZD-032菌株发酵转化中药及其增效机理的研究,2011/01-2013/12。
8. 横向项目,H20150014,基于糖尿病肾病防治的玉竹高异黄酮黑芝麻油,2014/12-2016/12。
9. 横向项目,H20140432,旋转刀头锋利度及寿命检测技术,2014/01-2014/12。
10. 浙江省自然科学基金面上项目,Y2090436,用于抗肿瘤活性成分分离的分子印记新技术及其仿生识别应用,2010/01-2012/12,6万元。
11. 浙江大学基本科研业务费专项资金项目,天麻对灰树花多糖合成及其抑瘤增效机理的研究,2011/06-2012/06。
12. 中国博士后科学基金,Y20080348,乌饭树抑菌活性成分对UV-B辐射的响应及构效关系研究,2008/09-2009/12。
期刊论文
(一)第一作者或通讯作者SCI论文
1. Qingbo Liu, Wei Li*, Kazuya Nagata, Hongwei Fu*, Shunpei Okada, Ikumi Tanabe, Yumi Kobori, Koji Higai, Wada Norie, Tatsunori Sasaki, Yoshihisa Asada, Huanxin Zhao, Hong Bai, Kazuo Koike, Isolation, Structural Elucidation, and Liquid Chromatography−Mass Spectrometry Analysis of Steroidal Glycosides from Polygonatum Odoratum, Journal of Agricultural and Food Chemistry, 2018, 66 (2): 521-531, impact factor: 3.412.(Q1区)
2. Hong-wei Fu, Lin Zhang, Tao Yi, Yu-lin Feng, Jing-kui Tian*, Two new guaiane-type sesquiterpenoids from the fruits of Daucus carota L., Fitoterapia, 2010, 81 (5): 443-446, impact factor: 2.642.
3. Hong-wei Fu, Lin Zhang, Tao Yi, Run-ze Chen, Xin Wang and Jing-kui Tian*, Two New Guaiane type Sesquiterpene Glycosides from the fruits of Daucus carota L., Chemical and Pharmaceutical Bulletin, 2010, 58 (1): 125-128, impact factor: 1.258.
4. Hong-wei Fu, Lin Zhang, Tao Yi, Yu-lin Feng, and Jing-kui Tian*, Guaiane type sesquiterpenes and other constituents from Daucus carota L., Biochemical Systematics and Ecology, 2010, 38 (3): 309-312, impact factor: 0.847.
5. Hong-wei Fu, Ying Guo, Wei Li*, Deqiang Dou*, A new angelloylated triterpenoid saponin from the husks of Xanthoceras sorbifolia Bunge., Journal of Natural Medicines, 2010, 64 (1): 80-84, impact factor: 1.920.
6. Hong-Wei Fu, Lin Zhang, Tao Yi, Yu-Lin Feng and Jing-Kui Tian*, One New Guaiane-type Sesquiterpene Glycoside from the fruits of Daucus carota L., Pharmazie, 2010, 1: 69-71, impact factor: 1.016.
7. Hong-Wei Fu, Lin Zhang, Tao Yi and Jing-Kui Tian*, A New Sesquiterpene from the Fruits of Daucus carota L., Molecules, 2009, 14 (8): 2862-2867, impact factor: 3.098.
8. Tao Yi, Lin Zhang, Hong-Wei Fu*, Shi-Lin Yang and Jing-Kui Tian*, Two New Guaiane Sesquiterpenes from the Fruits of Daucus carota, Helvetica Chimca Acta, 2009, 92 (12): 2769-2773, impact factor: 1.081
9. Hong-wei Fu, Hai-long Zhang, Yue-hu Pei*, A new coumestan from Arachis hypogaea L., Chinese Chemical Letters, 2005, 16(7): 918-920, impact factor: 2.631.
(二)其他SCI论文
10. Wen Zheng, Xianghong Lu, Zhirong Fu, Lin Zhang, Ximin Li, Xiaobao Xu, YinaRen, Yongzhuang Lu, Hongwei Fu, Jingkui Tian*, Identification of candidate synovial membrane biomarkers after Achyranthes aspera treatment for rheumatoid arthritis, Biochimica et Biophysica Acta, 2016, 1864 (3): 308–316, impact factor: 2.609. (Q2区)
11. Na Wang, Tian-xiang *Wu, Zhang Yong; Xiao-bao Xu, Sha Tan, Hong-wei Fu, Experimental analysis on the main contents of Rhizoma gastrodiae extract and inter-transformation throughout the fermentation process of Grifola frondosa, Archives of Pharmacal Research, 2013, 36 (3): 314-321, impact factor: 2.33. (Q3区)
12. Ming-yao Sun, Xi-da Gu, Hong-wei Fu, Lin Zhang, Run-ze Chen, Lei Cui, Long-hai Zheng, Da-wei Zhang, Jing-kui Tian*, Change of secondary metabolites in leaves of Ginkgo biloba L. in response to UV-B induction, Innovative Food Science and Emerging Technologies, 2010, 11 (4): 672-676, impact factor: 3.116.
13. Xi-da Gu, Ming-yao Sun, Lin Zhang, Hong-wei Fu, Lei Cui, Run-ze Chen, Da-wei Zhang and Jing-kui Tian*, Change of Secondary Metabolites in Leaves of Morus alba L. after UV-B Induction, Molecules, 2010, 15 (5): 2980-2993, impact factor: 3.098.
14. Wei Li*, Hong-wei Fu, Hong Bai, and Kazuo Koike, Triterpenoid Saponins from the Roots of Rubus ellipticus var. obcordatus, Journal of Natural Products, 2009, 72 (10): 1755-1760, impact factor: 3.885.
15. Nan Wang, Zhan-lin Li, Dan-dan Song, Wei Li, Hong-wei Fu, Kazuo Koike, Yue-hu Pei, Yong-kui Jing and Hui-ming Hua*, Lanostane-Type Triterpenoids from the Roots of Kadsura coccinea, Journal of Natural Products, 2008, 71 (6): 990-994, impact factor: 3.885.
16. Wei Li, Kun Wei, Hong-wei Fu, Kazuo Koike*, Structure and Absolute Configuraton of Clerodane Diterpene Glycosides and A Rearranged Cadinane Sesquiterpene Glycoside from Stems of Tinospora sinensis, Journal of Natural Products, 2007, 70 (12): 1971-1976, impact factor: 3.885.
17. Ke Ma, Wei Li, Hong-wei Fu, Kazuo Koike, Wen-han Lin, Leen van Ofwegen, Hong-zheng Fu*, New 4α-methyl Steroids from A Chinese Soft Coral Nephthea sp., Steroids, 2007, 72 (14): 901-907, impact factor: 2.523.
18. Fang Li, Wei Li*, Hong-wei Fu, Qingbo Zhang, and Kazuo Koike, Pancreatic lipase-inhibiting triterpenoid saponins from fruits of Acanthopanax senticosus, Chemical and Pharmaceutical Bulletin, 2007, 55 (7): 1087-1089, impact factor: 1.258.
19. Yue-hu Pei,* Rui-fen Li, Hong-wei Fu, Jing Wang, Yu-zhi Zhou, A new isoflavone glucoside from Astragralus membranaceus var. mongholicus, Fitoterapia, 2007, 78 (7-8): 602-604, impact factor : 2.642.
20. Hong-quan Yin, Hui-ming Hua, Hong-wei Fu, Yue-hu Pei*, New Sesquiterpen Lactone with the Sulfonic Acid group from Saussurea lappa., Journal of Asian Natural Products Research, 2007, 9 (7): 579-582, impact factor: 1.091.
21. Yong-Fu Huang, Li Tian, Hong-Wei Fu, Hui-Ming Hua, Yue-Hu Pei*, One new anthraquinone from marine Streptomyces sp. FX-58, Natural Product Research, 2006, 20(13): 1207-1210, impact factor: 1.928.
22. Hong-quan Yin, Hong-wei Fu, Hui-ming Hua, Xiu-lan Qi, Wen Li, Yi Sha, Yue-hu Pei*, Two new sesquiterpene lactones with the sulfonic acid group from Saussurea lappa, Chemical and Pharmaceutical Bulletin, 2005, 53(7): 841-842, impact factor: 1.258.
发明专利
1. 付红伟,张琳,甾体皂苷类化合物及其制备方法与应用,2017.11.30,中国,201711238192.X
2. 张琳,付红伟,杨丙贤,韩昊特,田景奎,陈梦,欧钰婷,一种基于南烛叶的天然着色剂的制备方法及其用途,2018.01.08,中国,201810016654.1
3. 田景奎,张琳,应弘梅,付红伟,王欣,田富饶,郑筱祥,利用大孔树脂制备细梗香草总皂苷提取物的方法及用途,2011.10.26,中国,ZL200910096786.0
4. 张琳,孙铭遥,田景奎,付红伟,谷希达,崔磊,陈润泽,田富饶,王欣,一种提高银杏叶药效成分含量的方法,2011.05.04,中国,ZL200910154119.3
5. 李巍、王英华、小池一男、付红伟、谢鹏,枸杞籽及其提取枸杞油后的残渣中提取α-葡萄糖苷酶活性抑制剂的方法及其用途,2015.08.19,中国,ZL201210347818.1