我的研究成果

1.     主持国家自然科学基金青年基金项目，三疣梭子蟹两种含不同关键氨基酸基序C型凝集素的糖识别机制研究, 26万元

2.     主持浙江省自然科学基金，三疣梭子蟹C型凝集素免疫功能及非己识别机制研究， 7万元

3.     主持中国博士后科学基金一等资助，8万元

4.     主持国家海洋局第二海洋研究所中央级公益性科研院所基本科研业务费专项，10万

5.     参与国家自然科学基金委面上项目，副溶血弧菌T3SS2效应蛋白VPA1324操控宿主cdG免疫信号通路的肠毒性机制, 64万元

6.     参与国家自然科学基金委青年项目，长牡蛎吞噬细胞鉴定及吞噬作用机制研究, 26万元

7.     参与国家自然科学基金委青年项目，低温条件下灿烂弧菌JZ6致病性的初步研究, 20万元

发表主要论文和著作:

1.     Mengmeng Huang, Tao Zhou, Yuehong Wu, Hui Fei, Gaoyang Wang, Zhi Li, Yutong Lei, Qian Liu, Cong Sun, Zhengbing Lv*, Xue-Wei Xu*, Characterisation and functional comparison of single-CRD and multidomain containing galectins CgGal-2 and CgGal-3 from oyster Crassostrea gigas, Fish and Shellfish Immunology

2.     Mengmeng Huang, Changkao Mu, Yuehong Wu, Fei Ye, Dan Wang, Cong Sun, Zhengbing Lv, Bingnan Han, Chunlin Wang*, Xue-Wei Xu* The functional characterization and comparison of two single CRD containing C-type lectins with novel and typical key motifs from Portunus trituberculatus, Fish and Shellfish Immunology.

3.     Mengmeng Huang，Lingling Wang，Huan Zhang，Chuanyan Yang，Rui Liu，Jiachao Xu，Zhihao Jia，Linsheng Song* The sequence variation and functional differentiation of CRDs in a scallop multiple CRDs containing lectin，Developmental and Comparative Immunology.

4.     Meng-Meng Huang*, Li-Li Guo*, Yue-Hong Wu, Hong Cheng, Chun-Sheng Wang, Min Wu, Xue-Wei Xu1, Pseudooceanicola lipolyticus, a marine alphaproteobacterium isolated from seawater, International Journal of Systematic and Evolutionary Microbiology.

5.     Jialong Yang*, Mengmeng Huang*, Huan Zhang, Lingling Wang, Hao Wang, Leilei Wang, Limei Qiu, Linsheng Song, CfLec-3 from scallop: an entrance to non-self recognition mechanism of invertebrates C-type lectin. Scientific Reports. (共同一作)

6.     Mengmeng Huang, Huan Zhang, Shuai Jiang, Lingling Wang*, Rui Liu, Qilin Yi, Linsheng Song*, An EPD/WSD motifs containing C-type lectin from Argopectens irradians recognizes and binds microbes with broad spectrum. Fish and Shellfish Immunol.

7.     Mengmeng Huang, Lingling Wang, Jialong Yang, Huan Zhang, Leilei Wang, Linsheng Song*, A four-CRD C-type lectin from Chlamys farreri mediating nonself-recognition with broader spectrum and opsonization. Developmental and Comparative Immunology.

8.     Mengmeng Huang, Xiaoyan Song, Jianmin Zhao, Changkao Mu, Lingling Wang*, Huan Zhang, Zhi Zhou, Xiaolin Liu, Linsheng Song*, A C-type lectin (AiCTL-3) from bay scallop Argopecten irradians with mannose/galactose binding ability to bind various bacteria. Gene