代表性论文（第一作者&通讯作者）

(44) Jianhua Tang, Zuguang Yang, Yufei Song, Zhengkai Chen*, Xiao-Feng Wu*, Palladium-catalyzed norbornene-mediated dehydrogenative annulation of 3-iodochromones with trifluoroacetimidoyl chlorides for the construction of trifluoromethyl-substituted chromeno[2,3-c]quinolin-12-ones. Mole. Catal. 2022, 524, 112320. (IF = 5.062)

(43) Shu-Ning Lu, Yue Sun, Jiajun Zhang, Zhengkai Chen*, Xiao-Feng Wu*, Metal-free Synthesis of 5-trifluoromethyl-1,2,4-triazoles via elemental sulfur promoted oxidative cyclization of trifluoroacetimidohydrazides with benzylic and aliphatic amines. Mole. Catal. 2022, 524, 112336. (IF = 5.062)

(42) Ruizhe Wang, Xinyu Wang, Shuai Mao*, Yahao Zhao, Bo Yuan, Xue-Yan Yang, Jianjun Li*, Zhengkai Chen*, Metal-free Photochemical C-Se Cross-Coupling of Aryl Halides with Diselenides. Adv. Synth. Catal. 2022, 364, 1607-1612. (IF = 5.837)

(41) Hefei Yang, Le-Cheng Wang, Yu Zhang, Dongling Zheng, Zhengkai Chen*, Xiao-Feng Wu*, Controllable access to trifluoromethyl-containing indoles and indolines: Palladium-catalyzed regioselective functionalization of unactivated alkenes with trifluoroacetimidoyl chlorides. Chem. Sci. 2022, 13, 3526-3532. (IF = 9.825)

(40) Yu Zhang, Zuguang Yang, Zhengkai Chen*, Leifang Liu*, Xiao-Feng Wu*, Copper-Catalyzed Decarbonylative Cyclization of Isatins and Trifluoroacetimidohydrazides for the Synthesis of 2-(5-Trifluoromethyl-1,2,4-triazol-3-yl)anilines. Adv. Synth. Catal. 2022, 364, 1044-1049. (IF = 5.837)

(39) Hefei Yang, Jiajun Zhang, Zhengkai Chen*, Xiao-Feng Wu*, TFBen (Benzene-1,3,5-triyl triformate): A Powerful and Versatile CO Surrogate. Chem. Rec. 2022, 22, e202100220. (IF = 6.771)

(38) Shu-Ning Lu, Hefei Yang, Jiajun Zhang, Zhengkai Chen*, Xiao-Feng Wu*, Oxidative Cyclization of Trifluoroacetimidohydrazides with D‑Glucose for the Metal-free Synthesis of 3-Trifluoromethyl-1,2,4-triazoles. Adv. Synth. Catal. 2021, 363, 4982-4987. (IF = 5.837)

(37) Jiajun Zhang, Jianhua Tang, Zhengkai Chen*, Xiao-Feng Wu*, Elemental Sulfur and Dimethyl Sulfoxide-Promoted Oxidative Cyclization of Trifluoroacetimidohydrazides with Methylhetarenes for the Synthesis of 3-Hetaryl-5-trifluoromethyl-1,2,4-triazoles. Chin. J. Chem. 2021, 39, 3443-3447. (IF = 6.0)

(36) Jianhua Tang, Jiajun Zhang, Yu Zhang, Zhengkai Chen*, Xiao-Feng Wu*, Palladium-Catalyzed Three-Component Carbonylative Synthesis of 5-Trifluoromethyl-1,2,4-triazoles from Trifluoroacetimidohydrazides and Aryl Iodides. Org. Chem. Front. 2021, 8, 6089-6094. (IF = 5.281)

(35) Tiefeng Xu, Yu Zhang, Lili Yi, Wangyang Lu*, Zhengkai Chen*, Xiao-Feng Wu*, Efficient Synthesis of 2-Trifluoromethyl-benzimidazoles via Cascade Annulation of Trifluoroacetimidoyl Chlorides and Amines Based on a Heterogeneous Copper Doped g-C₃N₄ Catalyst. Mole Catal 2021, 509, 111767. (IF = 5.062)

(34) Yufei Song, Le-Cheng Wang, Shiying Du, Zhengkai Chen*, Xiao-Feng Wu*, The Cascade Coupling/Iodoaminocyclization Reaction of Trifluoroacetimidoyl Chlorides and Allylamines: Metal-free Access to 2-Trifluoromethyl-imidazolines. Org. Biomol. Chem. 2021, 8, 6115-6119. (IF = 3.876)

(33) Hefei Yang, Shu-Ning Lu, Yufei Song, Zhengkai Chen*, Xiao-Feng Wu*, Copper-mediated [3+2] cycloaddition of trifluoroacetimidoyl chlorides and N-isocyanoiminotriphenylphosphorane for the synthesis of 3-trifluoromethyl-1,2,4-triazoles. Org. Chem. Front. 2021, 8, 5040-5044. (IF = 5.281)

(32) Jiajun Zhang, Tian-Hui Xu, Zhengkai Chen*, Xiao-Feng Wu*, Metal-free oxidative cyclization of trifluoroacetimidohydrazides with methylhetarenes: a facile access to 3-hetaryl-5-trifluoromethyl-1,2,4-triazoles. Org. Chem. Front. 2021, 8, 4490-4495. (IF = 5.281)

(31) Hefei Yang, Tian-Hui Xu, Shu-Ning Lu, Zhengkai Chen*, Xiao-Feng Wu*, Synthesis of 5-trifluoromethyl-1,2,3-triazoles via base-mediated cascade annulation of diazo compounds with trifluoroacetimidoyl chlorides. Org. Chem. Front. 2021, 8, 3440-3445. (IF = 5.281)

(30) Jiajun Zhang, Jianhua Tang, Zhengkai Chen*, Xiao-Feng Wu*, Synthesis of 5-Trifluoromethyl-1,2,4-triazoles from Metal-free Mediated Annulation of Trifluoroacetimidohydrazides and Methyl Ketones. Adv. Synth. Catal. 2021, 363, 3060-3069. (IF = 5.837)

(29) Shiying Du, Zuguang Yang, Jianhua Tang, Zhengkai Chen*, Xiao-Feng Wu*, Synthesis of 3H-1,2,4-triazol-3-ones via NiCl₂-promoted cascade annulation of hydrazonoyl chlorides and sodium cyanate. Org. Lett. 2021, 23, 2359-2363. (IF = 6.005)

(28) Le-Cheng Wang, Yu Zhang, Zhengkai Chen*, Xiao-Feng Wu*, Palladium-Catalyzed Carbonylative Synthesis of 2-(Trifluoromethyl)quinazolin-4(3H)-ones from Trifluoroacetimidoyl Chlorides and Nitro Compounds. Adv. Synth. Catal. 2021, 363, 1417-1426. (IF = 5.837)

(27) Hefei Yang, Shu-Ning Lu, Zhengkai Chen*, Xiao-Feng Wu*, Silver-Mediated [3+2] Cycloaddition of Azomethine Ylides with Trifluoroacetimidoyl Chlorides for the Synthesis of 5-Trifluoromethyl-imidazoles. J. Org. Chem. 2021, 86, 4361-4370. (IF = 4.354)

(26) Shiying Du, Wei-Feng Wang, Yufei Song, Zhengkai Chen*, Xiao-Feng Wu*, Palladium-Catalyzed Cascade Carbonylative Synthesis of 1,2,4-Triazol-3-ones from Hydrazonoyl Chlorides and NaN₃. Org. Lett. 2021, 23, 974-978. (IF = 6.005)

(25) Zhengkai Chen, Shiying Du, Jiajun Zhang, Xiao-Feng Wu*, From 'Gift' to gift: Producing Organic Solvents from CO_2. Green Chem. 2020, 22, 8169-8182. (IF = 10.182)

(24) Hefei Yang, Le-Cheng Wang, Wei-Feng Wang, Zhengkai Chen*, Xiao-Feng Wu*, Palladium-Catalyzed Cascade Carbonylative Cyclization Reaction of Trifluoroacetimidoyl Chlorides and 2-Iodoanilines: Toward 2-(Trifluoromethyl)quinazolin-4(3H)-ones Synthesis. Chemistryselect 2020, 5, 11072-11076. (IF = 2.109)

(23) Shiying Du, Le-Cheng Wang, Zuguang Yang, Zhengkai Chen*, Xiao-Feng Wu*, Synthesis of 5-Trifluoromethyl-1,2,4-triazoles from FeCl₃-Mediated Cascade Annulation of Trifluoroacetimidoyl Chlorides with Hydrazides. Adv. Synth. Catal. 2020, 362, 5130-5134. (IF = 5.837)

(22) Zhengkai Chen, Le-Cheng Wang, Jiajun Zhang, Xiao-Feng Wu*, Palladium-Catalyzed Three-Component Carbonylative Synthesis of 2-(Trifluoromethyl)quinazolin-4(3H)-ones from Trifluoroacetimidoyl Chlorides and Amines. Org. Chem. Front. 2020, 7, 2499-2504. (IF = 5.281)

(21) Le-Cheng Wang, Shiying Du, Zhengkai Chen*, Xiao-Feng Wu*, FeCl₃-Mediated Synthesis of 2-(Trifluoromethyl)quinazolin-4(3H)-ones from Isatins and Trifluoroacetimidoyl Chlorides. Org. Lett. 2020, 22, 5567-5571. (IF = 6.005)

(20) Zhengkai Chen, Le-Cheng Wang, Xiao-Feng Wu*, Carbonylative synthesis of heterocycles involving diverse CO surrogates. Chem. Commun. 2020, 56, 6016-6030. (IF = 6.222)

(19) Sipei Hu, Hefei Yang, Zhengkai Chen*, Xiao-Feng Wu*, Base-mediated [3+2] annulation of trifluoroacetimidoyl chlorides and isocyanides: an improved approach for regioselective synthesis of 5-trifluoromethyl-imidazoles. Tetrahedron 2020, 76, 131168. (IF = 2.457)

(18) Zhengkai Chen, Wei-Feng Wang, Hefei Yang, Xiao-Feng Wu*, Palladium-Catalyzed Four-Component Carbonylative Cyclization Reaction of Trifluoroacetimidoyl Chlorides, Propargyl Amines, and Diaryliodonium Salts: Access to Trifluoromethyl-Containing Trisubstituted Imidazoles. Org. Lett. 2020, 22, 1980-1984. (IF = 6.005)

(17) Zhengkai Chen, Sipei Hu, Xiao-Feng Wu*, Trifluoroacetimidoyl halides: a potent synthetic origin. Org. Chem. Front. 2020, 7, 223-254. (IF = 5.281)

(16) Sipei Hu, Zuguang Yang, Zhengkai Chen*, Xiao-Feng Wu*, Metal-Free Synthesis of 5-Trifluoromethyl-1,2,4-Triazoles from Iodine-Mediated Annulation of Trifluoroacetimidoyl Chlorides and Hydrazones. Adv. Synth. Catal. 2019, 361, 4949-4954. (IF = 5.837)

(15) Sipei Hu, Shiying Du, Zuguang Yang, Lingfang Ni, Zhengkai Chen*, Synthesis of Multi-substituted Dihydropyrazoles by Copper-Mediated [4+1] Cycloaddition Reaction of N-Sulfonylhydrazones and Sulfoxonium Ylides. Adv. Synth. Catal. 2019, 361, 3124-3136. (IF = 5.837)

(14) Sipei Hu, Shiying Du, Yunjie Yao, Zuguang Yang, Hongjun Ren*, Zhengkai Chen*, Iodine-Mediated Multicomponent Synthesis of 3-Sulfenylimidazo[1,2-a]pyridines from 2-Aminopyridines, Ketones, and Sulfonyl Hydrazides. Synlett 2019, 30, 625-629. (IF = 2.454)

(13) Gangjian Cao, Zhengkai Chen*, Jinyu Song, Jianfeng Xu, Maozhong, Miao, Hongjun Ren*, Oxidant-Mediated Nitrogenation and Recyclization of Imidazo[1,2-a]pyridines with Sodium Azide: Synthesis of 4H-Pyrido[1,2-a][1,3,5]triazin-4-ones. Adv. Synth. Catal. 2018, 360, 881-886. (IF = 5.837)

(12) Zhengkai Chen, Nai-Wei Liu, Michael Bolte, Hongjun Ren, Georg Manolikakes*, Visible-light mediated 3-component synthesis of sulfonylated coumarins from sulfur dioxide. Green Chem., 2018, 20, 3059–3070. (IF = 10.182)

(11) Zhengkai Chen*, Zhubo Liu, Gangjian Cao, Hongli Li, Hongjun Ren*, Recent Advances in Multicomponent Synthesis of 1,4,5-Trisubstituted 1,2,3-Triazoles. Adv. Synth. Catal. 2017, 359, 202-224. (IF = 5.837)

(10) Zhengkai Chen*, Hongli Li, Weipeng Dong, Maozhong Miao, Hongjun Ren*, I₂-Catalyzed Oxidative Coupling Reactions of Hydrazones and Amines and the Application in the Synthesis of 1,3,5-Trisubstituted 1,2,4-Triazoles. Org. Lett. 2016, 18, 1334-1337. (IF = 6.005 Abstracted by Organic Chemistry Portal)

(9) Zhengkai Chen*, Gangjian Cao, Jinyu Song, Hongjun Ren*,Recent Developments in Azide-Free Synthesis of 1,2,3-Triazoles. Chin. J. Chem. 2017, 35, 1797-1807. (IF = 6.0)

(8) Lili Zhang, Zhengkai Chen*, Hongli Li, Wenguang Yin, Jianfeng Xu, Maozhong, Miao, Hongjun Ren, Transition metal-free tandem pyridinyl–allyl–allyl cross-coupling reaction. Synth. Commun. 2017, 47, 1668-1675. (IF = 2.007)

(7) Zhengkai Chen*, Gangjian Cao, Fengjin Zhang, Hongli Li, Jianfeng Xu, Maozhong Miao, Hongjun Ren*, Metal-Free Mediated C-3 Methylsulfanylation of Imidazo[1,2-a]-pyridines with Dimethyl Sulfoxide as a Methylsulfanylating Agent. Synlett 2017, 28, 1795-1800. (IF = 2.454)

(6) Zhengkai Chen*, Hongli Li, Gangjian Cao, Jianfeng Xu, Maozhong Miao, Hongjun Ren*, Copper-Catalyzed Double C–N Bond Formation for the Synthesis of Diverse Benzimidazoles from N-Alkyl-2-iodoaniline and Sodium Azide. Synlett 2017, 28, 504-508. (IF = 2.454)

(5) Zhengkai Chen, Binjie Wang, Jitan Zhang, Wenlong Yu, Zhanxiang Liu, Yuhong Zhang*, Transition Metal-Catalyzed C-H Bond Functionalizations by the Use of Diverse Directing Groups. Org. Chem. front. 2015, 2, 1107-1295. (IF = 5.281, 943 次引用; 高被引论文)

(4) Zhengkai Chen, Qiangqiang Yan, Zhanxiang Liu, Yiming Xu,, Yuhong Zhang*, Copper-Mediated Synthesis of 1,2,3-Triazoles from N-Tosylhydrazones and Anilines. Angew. Chem. Int. Ed. 2013, 52, 13324-13328. (IF = 15.336, Highlighted by Synfacts 2014, 10, 19.)

(3) Zhengkai Chen, Qiangqiang Yan, Hong Yi, Zhanxiang Liu, Aiwen Lei, Yuhong Zhang*, Efficient Synthesis of 1,2,3-Triazoles by Copper-Mediated C-N and N-N Bond Formation Starting From N-Tosylhydrazones and Amines. Chem. Eur. J. 2014, 20, 13692-13697. (IF = 5.236)

(2) Zhengkai Chen, Qiangqiang Yan, Zhanxiang Liu, Yuhong Zhang*, Metal-Free C-N and N-N Bond Formation: Synthesis of 1,2,3-Triazoles from Ketones, N-Tosylhydrazines, and Amines in One Pot. Chem. Eur. J. 2014, 20, 17635-17639. (IF = 5.236)

(1) Zhengkai Chen, Weijun Yang, Lijun Xu, Lili Zhang, Maozhong Miao, Hongjun Ren*, BF₃•OEt₂-Promoted Tandem O-Arylation/Hydroxylation: Efficient Synthesis of 2-Hydroxyflavanones from Triazenylaryl-Substituted Diketones. Eur. J. Org. Chem. 2013, 7411-7420. (IF = 3.021)

专著

1 Zhengkai Chen, Hongjun Ren, SOLVENTS AS REAGENTS IN ORGANIC SYNTHESIS: REACTIONS AND APPLICATIONS (Ed by Xiao-Feng Wu, WILEY-VCH, 2018) Chapter: The Applications of Water as Reagents in Organic Synthesis

2 Zhengkai Chen, Xiao-Feng Wu, The Chemical Transformations of C1 Compounds (Ed by Xiao-Feng Wu, Kuiling Ding, Buxing Han, Zhongmin Liu, WILEY-VCH, 2022) Chapter: Chemical Transformations of Methanol

获得奖项

张玉红，刘占祥，陈铮凯，黄乐浩，骆成才，过渡金属催化的绿色反应研究，浙江省自然科学奖二等奖 (2017)

发明专利

10 吴小锋，陈铮凯，杨合肥，申请号：202010936182.9, 一种2-三氟甲基取代的喹唑啉酮衍生物的制备方法（已申请）

9 陈铮凯，杜世英，吴小锋，申请号：202010936155.1, 一种5-三氟甲基取代的1,2,4-三氮唑衍生物的制备方法（已申请）

8 吴小锋，陈铮凯，王乐程，专利号：ZL 202010556190.0, 一种2-三氟甲基取代的喹唑啉酮化合物的制备方法（已授权）

7 吴小锋，陈铮凯，王伟丰，杨合肥，专利号：ZL 202010055490.0, 一种2-三氟甲基取代的咪唑化合物的制备方法（已授权）

6 陈铮凯，胡思培，杨祖光，专利号：ZL 201910692941.9, 一种5-三氟甲基取代的1,2,4-三氮唑化合物的制备方法（已授权）

5 陈铮凯，胡思培，倪铃芳，专利号：ZL 201811295056.9, 一种分子碘促进的一锅法合成3位硫基取代咪唑并[1,2-a]吡啶化合物的方法（已授权）

4 陈铮凯，胡思培，杨祖光，倪铃芳，田青华，专利号：ZL 201910269787.4, 一种多取代的4,5-二氢吡唑化合物的制备方法（已授权）

3 任红军，陈铮凯，董卫朋，专利号：ZL 201610169703.6, 一种m-PEG聚合物的制备方法（已授权）

2 陈铮凯，曹刚剑，任红军，专利号：ZL 201711063609.3, 一种吡啶并[1,2-a][1,3,5]-三嗪-4-酮化合物的制备方法（已授权）

1 陈铮凯，李红礼，任红军，专利号：ZL 201610058811.6, 一种1,3,5-三取代的1,2,4-三氮唑化合物的制备方法（已授权）