研究成果
项目：
1. 主持国家自然科学基金青年基金，电刺激调控神经干细胞在氧化铱/聚多巴胺/Laminin仿生涂层上的定向分化研究，51502265，2016.01-2018.12
2. 主持浙江省自然科学基金青年基金，抗增生/促内皮多功能微纳结构化涂层对冠脉支架再狭窄的抑制作用研究，LQ16E020006，2016.01-2018.12
3. 参与（2/9）国家自然科学基金面上项目，多级有序石墨烯凝胶构建神经支架及对干细胞定向分化与神经再生的导向作用研究，51572242，2016.01-2019.12
4. 参与横向课题（2/10），ZSTU-Dentium功能性生物材料与再生医学联合研究中心，2014.01-2017.01
论文：
1. Chen C, Lee I-S*, Zhang S M, Yang H C. Biomimetic apatite formation on calcium phosphate-coated titanium in Dulbecco’s phosphate-buffered saline solution containing CaCl2 with and without fibronectin. Acta Biomaterialia, 2010, 6, 2274-2281. (IF2014 = 6.025, SCI 1档, Top期刊)
2. Chen C, Qiu Z-Y, Zhang S M, Lee I-S*. Biomimetic fibronectin/mineral and osteogenic growth peptide/mineral composites synthesized on calcium phosphate thin films. Chemical Communications, 2011, 47, 11056-11058. (IF2014 = 6.834, SCI 2档, Top期刊)
3. Chen C, Zhang S M, Lee I-S*. Immobilizing bioactive molecules onto titanium implants to improve osseointegration. Surface & Coatings Technology, 2013, 228, S312-S317. (IF2014 = 1.998, SCI 3档)
4. Chen C, Yang W, Wang D T, Chen C L, Zhuang Q Y, Kong X D*. A modified spontaneous emulsification solvent diffusion method for the preparation of curcumin-loaded PLGA nanoparticles with enhanced in vitro anti-tumor activity. Frontier of Materials Science, 2014, 8, 332-342. (IF2014 = 1, SCI 4档)
5. Chen C, Kong X D, Zhang S M, Lee I-S*. Characterization and in vitro biological evaluation of mineral/osteogenic growth peptide nanocomposites synthesized biomimetically on titanium. Applied Surface Science, 2015, 334, 62-68. (IF2014 = 2.711, SCI 2档, Top期刊)
6. Chen C, Li H, Kong X D, Zhang S M, Lee I-S*. Immobilizing osteogenic growth peptide with and without fibronectin on a titanium surface: effects of loading methods on mesenchymal stem cell differentiation. International Journal of Nanomedicine, 2015, 10, 283-295. (IF2014 = 4.383, SCI 2档)
7. Chen C, Yang H C, Lee I-S*. Immobilizing hydroxycholesterol with apatite on titanium surfaces to induce ossification. Biomaterials Research, 2014, 18, 16.
8. 王丹彤，陈超龙，庄青叶，杨卫，陈岑*. 水溶性大分子调控合成纳米碳酸钙研究进展. 材料导报, 2015, 29, 20-25. (二级期刊)
9. Chen C, Kong X D, Lee I-S*. Modification of surface/neuron interfaces for neural cell-type specific responses: a review. Biomedical Materials. (Accepted) (IF2014 = 3.697, SCI 2档)
10. Chen C, Han H F, Yang W, Ren X Y, Kong X D*. Polyethyleneimine modified calcium carbonate nanoparticles for p53 gene delivery. Regenerative Biomaterials. (Accepted)
11. Zhao R B, Yang X Y, Chen C, Chen K, Wang S B, Xie C G, Ren X Y, Kong X D*. The anti-tumor effect of p53 gene-loaded hydroxyapatite nanoparticles in vitro and in vivo. Journal of Nanoparticle Research, 2014, 16, 2353. (IF2014 = 2.184, SCI 2档)
12. Qiu Z-Y, Chen C, Wang X-M, Lee I-S*. Advances in the surface modification techniques of bone-related implants for last 10 years. Regenerative Biomaterials, 2014, 67-79.
13. Liu F, Meng Q Y, Chen C, Cui F Z, Liu Y*, Lee I-S*. Loading collagen and hydroxycholesterol within biomimetic mineral onto titanium: synergistically promoting osteogenic expression of mesenchymal stem cells. Journal of Biomaterials and Tissue Engineering, 2015, 5, 164-171. (IF2014 = 2.066, SCI 4档)
14. 赖文，陈岑，叶婷，章赛赛，吕晓露，孔祥东．无齿相手蟹体表刚毛的结构及其功能．浙江理工大学学报. (已接收)
专利申请：
1. 孔祥东, 赖文, 陈岑, 李麟涉, 姚菊明, 江国华. 一种中空羟基磷灰石微球及其制备方法. (201510351925.5)
2. 孔祥东, 徐晓春, 赖文, 陈岑, 姚菊明, 陈侃. 一种球状纳米羟基磷灰石-siRNA复合物及其制备方法.
3. 孔祥东, 姚晨雪, 陈岑, 李麟涉, 赖文, 江国华, 姚菊明. 一种医用蚕丝纸及其制备方法.
