研究成果
科研教学项目
1. 卫星RNA选择性抑制CMV RNA1和RNA2复制的结构基础及其作用机制, 国家自然科学基金（31870144），2019.01-2022.12，59万（主持）
2. 植物液泡脂质调控CMV复制的分子机制，国家自然科学基金（31600125），2017.01-209.12，22万（1st参加）
3. CMV复制酶组分1a蛋白调控亚基因组RNA4A合成的分子机制，国家自然科学基金（31470007）， 2015.01-2016.12，30万（主持）
4. 卫星RNA和协生病毒与CMV的互作对CMV诱导拟南芥抗蚜虫反应的影响及其途径,国家自然科学基金（31170141），2012.01-2015.12，64万（主持）
5. Subversion of Ins0ect Resistance: A novel Role for a Plant Viral Silencing Suppressor. European FP7-Marie Curie International Incoming Fellowship (PIIF-GA-2009-236443), 2009.10-2011.09，约175万（主持）
6. CMV 2b蛋白致病关键氨基酸在RNA沉默通路中的作用方式和靶位,国家自然科学基金（30800043），2009.01-2011.12，20万（主持）
7. 外源AGO1蛋白特定片段对CMV 2b蛋白抗RNA沉默活性的干扰研究,浙江省自然科学基金（Y3080315），2009.01-2011.12，8万（主持）
8. 蜂源性降血压功能肽高效表达基因的筛选及优化,国家高技术发展研究计划（863计划）, 2008.01-2010.12，50万（主持）
专著论文
第一/通讯作者论文（*通讯作者）
1. He L, Wang Q, Gu Z, Liao Q, Palukaitis P, Du Z*. A conserved RNA structure is essential for a satellite RNA-mediated inhibition of helper virus accumulation. Nucleic Acids Research, 2019, gkz564, doi: 10.1093/nar/gkz564 . Top Journal（IF：11.14）
2. Du Z, Alekhina O, Vassilenko K, Simon A; Concerted action of two 3΄ cap-independent translation enhancers increases the competitive strength of translated viral genomes, Nucleic Acids Research, 2017, gkx643. Top Journal （IF：11.56）
3. Du Z*, Chen A, Chen W, Westwood J, Baulcombe DC, Carr JP*. Using a Viral Vector to Reveal the Role of MicroRNA159 in Disease Symptom Induction by a Severe Strain of Cucumber mosaic virus. Plant Physiology, 2014, 164:1378-1388. (IF:7.39) Top Journal (IF：7.4)
4. Du Z*, Chen A, Chen W, Liao Q, Zhang H, Bao Y, Roossinck MJ, Carr JP*. Nuclear-cytoplasmic partitioning of the Cucumber mosaic virus 2b protein determines the balance between its roles as a virulence determinant and RNA silencing suppressor. Journal of Virology, 2014, 88(10): 5228-5241. (IF:4.68) Top Journal （IF：5.2）
5. Liao Q, Tu Y, Carr J.P*, Du Z*. An improved cucumber mosaic virus-based vector for efficient decoying of plant microRNAs. Scientific Reports 2015, 5:13178. (IF: 5.58)
6. Gao S, Lu J, Cheng X, Gu Z, Liao Q, Du Z*. Heterologous replicase from cucumoviruses can replicate viral RNAs, but is defective in transcribing subgenomic RNA4A or facilitating viral movement. Viruses. 2018,10 (11). pii: E590. doi: 10.3390/v10110590. (IF: 3.76)
7. 王妹妹, 陈文虎，廖乾生，杜志游*. MicroRNA 靶向病毒携带的microRNA 模拟靶序列对病毒的抑制作用. 生物化学与生物物理进展，2017, 44(2): 155-162. (SCI-E, 封面论文) (IF: 1.12)
8. Wang R, Du Z*, Liang Z*. The subcellular distribution of Cucumber mosaic virus LS2b protein, correlation between its nuclear localization and predicted nuclear localization signals. Physiological and Molecular Plant Pathology, 2017, 100:1-12.
9. Xu A, Zhao Z, Chen W, Liao Q, Chen J, Carr J, Du Z*. Self-interaction of the cucumber mosaic virus 2b protein plays a vital role in suppression of RNA silencing and induction of viral symptoms. Molecular Plant Pathology, 2013, 14(8), 803-812. (IF:3.89)
10. Du Z, Chen F, Zhao Z, Liao Q, Palukaitis P, Chen J. The 2b protein and the C-terminus of the 2a protein of cucumber mosaic virus subgroup I strains both play a role in viral RNA accumulation and induction of symptoms. Virology 2008, 380: 363-370. (IF:3.87)
11. Du Z-Y, Chen F-F, Liao Q-S, Zhang H-R, Chen Y-F, Chen J-S. The 2b ORFs encoded by subgroup IB strains of Cucumber mosaic virus induce different virulence on Nicotiana species. Journal of General Virology 2007, 88: 2596-2694. (IF: 3.37)
12. Du Z, Jin B, Liu W, Chen L, Chen J. Highly sensitive fluorescent-labeled probes and glass slide hybridization for the detection of plant RNA viruses and a viroid. Acta Biochimica et Biophysica Sinica 2007, 39(5): 326-334. (IF: 1.02)
13. Chen Y, Chen J, Zhang H, Tang X, Du Z*. Molecular evidence and sequence analysis of a natural reassortant between Cucumber mosaic virus subgroup IA and II strains. Virus Genes 2007, 35: 405-413. (IF: 2.43)
14. Du Z, Chen J, Hiruki C. Optimization and application of a multiplex RT-PCR for simultaneous detection of five potato viruses using 18S rRNA as an internal control. Plant Disease 2006, 90(2): 185-189. (IF: 2.91)
15. Du Z-Y, Chen J-S. Identification and grouping study of Potato virus X Hunan isolate. Virologica Sinica 2003, 18(2):119-123. (In Chinese)
共同作者论文
1. Li C, Du Z, Chen J. Structural and functional elucidation of AGO proteins. Chinese Journal of Biochemistry and Molecular Biology, 2009, 25(11): 969-976.
2. Li L, Tian Q, Du Z, Duns GJ, Chen J. A novel double-stranded RNA virus detected in Primula malacoides is a a plant-isolated partitivirus closely related to partitivirus infecting fungal species. Archive Virology, 2009, 164(4): 565-572.
3. Liao Q-S, Du Z-Y, Zhang H-R, Wu P, Zhu L-P, Chen J-S. Construction of infectious clone for cucumber mosaic virus pepper isolate. Scientia Agricultura Sinica 2008, 41(7): 1975-1982. (In Chinese)
4. Chen Y, Chen J, Zhang H, Tang X, Du Z. Molecular evidence and sequence analysis of a natural reassortant between Cucumber mosaic virus subgroup IA and II strains. Virus Genes 2007, 35: 405-413.
5. Liao Q, Zhu L, Du Z, Zeng R, Peng J, Chen J. Satellite RNA-mediated reduction of cucumber mosaic virus genomic RNAs accumulation in Nicotiana tabacum. Acta Biochimica et Biophysica Sinica 2007, 39(3):217-23.
6. Chen F-F, Du Z-Y, Liu X, Xie L, Chen J-S. Effect of Cucumber mosaic virus-encoded 2b protein on Photosynthesis and chloroplast structure of the host plant. Progress in Biochemistry and Biophysics 2007, 34(8): 889-896. (In Chinese)
7. Liao Q-S, Du Z-Y, Zhang H-R, Zhu L-P., Wu P, Chen J-S. Necrosis pathotype induced on Nicotiana glutinosa by infection of CMV-Cb7 related to RNA2. Progress in Biochemistry and Biophysics 2007, 34(8): 824-829. (In Chinese)
8. Lang Q-L, Chen J-S, Fu T-Z, Du Z-Y. Occurrence and molecular detection of Potato virus S (PVS) in Zhejiang province. Acta Phytopathology Sinica 2007, 32(2): 217-220. (In Chinese)
9. Feng J, Chen S, Tang X, Ding X, Du Z, Chen J. Quantitative determination of cucumber mosaic virus genome RNAs in virions by real-time reverse transcription-polymerase chain reaction. Acta Biochimica et Biophysica Sinica 2006, 38(10):669-676.
10. Gu Y, Du Z-Y, Lang Q-L, Chen J-S, He N-Y. Detection of Potato Spindle Tuber Viroid Using RNA Hybridized Chips. Chemical Research in Chinese Universities 2006, 27(11):2106-2109. (In Chinese)
11. Dong X-J*, Du Z-Y, Chen Z. Decolorization of Direct Black 22 by Aspergillus ficuum. Journal of Environmental Sciences 2001, 12(4): 472-475.
